Cellular proteostasis: degradation of misfolded proteins by lysosomes
نویسندگان
چکیده
منابع مشابه
Cellular proteostasis: degradation of misfolded proteins by lysosomes
Proteostasis refers to the regulation of the cellular concentration, folding, interactions and localization of each of the proteins that comprise the proteome. One essential element of proteostasis is the disposal of misfolded proteins by the cellular pathways of protein degradation. Lysosomes are an important site for the degradation of misfolded proteins, which are trafficked to this organell...
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ژورنال
عنوان ژورنال: Essays in Biochemistry
سال: 2016
ISSN: 0071-1365,1744-1358
DOI: 10.1042/ebc20160005